He studied painting at the Athens School of Fine Arts with teachers such as Nikiphoros Lytras and Konstantinos Volanakis, Georgios Roilos and Dimitrios Geraniotis. In 1907 he moved to Munich to continue his art studies with Otto Seitz. In 1910 he moved to Berlin, where he was taught from Max Liebermann. In 1917 he has already adopted elements of German expressionism movement in his own individual artistic style. He became very soon a respected artist in Germany and very soon he had his first contract with the Barhfeld gallery. In 1927 in Chemnitz there was a large exhibition of his work. Between 1929 and 1932 he travelled and lived in Paris with the financial support of the Barhfeld gallery. Due to the financial crisis across Europe he had to return to Eichenau near Munich, where he had built a house. Unfortunately, expressionism was gradually fading away in Germany with the rise of nazism in Germany’s politics.
In 1934 he returned to Greece. To his own disappointment he failed to take a position at the School of Fine Arts of Athens. Initially, Bouzianis was treated with hostility from the Athenian artistic circles who started to appreciate his oeuvre after his exhibition at Parnassos gallery in 1949.